RNF6 anticorps (C-Term)

N° du produit ABIN2774919

Détail du produit anti-RNF6 anticorps

Antigène: RNF6 (RING Finger Protein 6 (RNF6))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Cheval, Porc, Boeuf (Vache), Lapin, Chien, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF6 est non-conjugé

Application: Western Blotting (WB)

Séquence: VETGTLPILR LAHFFLLNES DDDDRIRGLT KEQIDNLSTR HYEHNSIDSE

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 86%, Rabbit: 86%, Rat: 92%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against RNF6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human RNF6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 685 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RNF6

Antigène: RNF6 (RING Finger Protein 6 (RNF6))

Autre désignation: RNF6 (RNF6 Produits)

Synonymes: anticorps 1200013I08Rik, anticorps 5730419H05Rik, anticorps AA537053, anticorps ring finger protein 6, anticorps ring finger protein (C3H2C3 type) 6, anticorps RNF6, anticorps Rnf6

Sujet: RNF6 contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
Alias Symbols: DKFZp686P0776
Protein Interaction Partner: UBE2D1, AR, LDB1, UBC, tat, UBE2H,
Protein Size: 685

Poids moléculaire: 78 kDa

ID gène: 6049

NCBI Accession: NM_005977, NP_005968

UniProt: Q9Y252

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Cell Size