RNF6 anticorps (C-Term)

N° du produit ABIN2774919

Cet anticorps Lapin Polyclonal détecte spécifiquement RNF6 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Chien, Cobaye, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour RNF6 anticorps (C-Term) (ABIN2774919)

Antigène: RNF6 (RING Finger Protein 6 (RNF6))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RNF6 anticorps

Épitope: C-Term

Fonction: RNF6 Antibody - C-terminal region

Séquence: VETGTLPILR LAHFFLLNES DDDDRIRGLT KEQIDNLSTR HYEHNSIDSE

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 86%, Rabbit: 86%, Rat: 92%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against RNF6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human RNF6

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43065-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur RNF6

Antigène: RNF6 (RING Finger Protein 6 (RNF6))

Autre désignation: RNF6

Sujet:

Background Information: RNF6 contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.

Gene Name: Ring finger protein (C3H2C3 type) 6

Alternative Symbols: DKFZp686P0776

Protein Name: E3 ubiquitin-protein ligase RNF6

Poids moléculaire: 78kDa

ID gène: 6049

NCBI Accession: NP_005968

UniProt: Q9Y252

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Cell Size