HOXB8 anticorps (Middle Region)

N° du produit ABIN2774996

Cet anticorps anti-HOXB8 Polyclonal Lapin (ABIN2774996) détecte spécifiquement HOXB8 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien et Porc.

Aperçu rapide pour HOXB8 anticorps (Middle Region) (ABIN2774996)

Antigène: HOXB8 (Homeobox B8 (HOXB8))

Reactivité: Humain, Souris, Rat, Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HOXB8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HOXB8 anticorps

Épitope: Middle Region

Fonction: HOXB8 Antibody - middle region

Séquence: FQNRRMKWKK ENNKDKFPSS KCEQEELEKQ KLERAPEAAD EGDAQKGDKK

Homologie: Dog: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against HOXB8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human HOXB8

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36028-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur HOXB8

Antigène: HOXB8 (Homeobox B8 (HOXB8))

Autre désignation: HOXB8

Sujet:

Background Information: HOXB8 belongs to the Antp homeobox family. It is a nuclear protein with a homeobox DNA-binding domain. This gene is included in a cluster of homeobox B genes located on chromosome 17. The protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.

Gene Name: Homeobox B8

Alternative Symbols: HOX2, HOX2D, Hox-2.4

Protein Name: Homeobox protein Hox-B8

Poids moléculaire: 27kDa

ID gène: 3218

NCBI Accession: NP_076921

UniProt: P17481