SP110 anticorps (C-Term)

N° du produit ABIN2775054

Cet anticorps Lapin Polyclonal détecte spécifiquement SP110 dans WB. Il présente une réactivité envers Humain, Chien et Porc.

Aperçu rapide pour SP110 anticorps (C-Term) (ABIN2775054)

Antigène: SP110 (SP110 Nuclear Body Protein (SP110))

Reactivité: Humain, Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SP110 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SP110 anticorps

Épitope: C-Term

Séquence: LITEMYTVAW FVRDMRLMFR NHKTFYKASD FGQVGLDLEA EFEKDLKDVL

Homologie: Dog: 79%, Human: 100%, Pig: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SP110. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human SP110

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 713 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SP110

Antigène: SP110 (SP110 Nuclear Body Protein (SP110))

Autre désignation: SP110

Sujet: The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. SP110 is a member of the SP100/SP140 family of nuclear body proteins and is a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation.The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.
Alias Symbols: FLJ22835, IFI41, IFI75, VODI, IPR1
Protein Interaction Partner: UBC, CEBPA, OSGEP, TSC22D1, TTR, TK1, SMN1, CDKN1A, ANXA7, ZSCAN9, NAP1L2, RUNX3, NDUFV2,
Protein Size: 713

Poids moléculaire: 81 kDa

ID gène: 3431

NCBI Accession: NM_080424, NP_536349

UniProt: Q9HB58