DHX8 anticorps (N-Term)

N° du produit ABIN2775203

Cet anticorps Lapin Polyclonal détecte spécifiquement DHX8 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cheval et Cobaye.

Aperçu rapide pour DHX8 anticorps (N-Term) (ABIN2775203)

Antigène: DHX8 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 8 (DHX8))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DHX8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DHX8 anticorps

Épitope: N-Term

Séquence: VKNGAEFTDS LISNLLRLIQ TMRPPAKPST SKDPVVKPKT EKEKLKELFP

Homologie: Cow: 100%, Dog: 88%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against DHX8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DHX8

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1220 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DHX8

Antigène: DHX8 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 8 (DHX8))

Autre désignation: DHX8

Sujet: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is highly homologous to yeast Prp22. This protein facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.
Alias Symbols: DDX8, HRH1, PRP22, PRPF22
Protein Interaction Partner: NUDCD1, UBC, LIN28A, XRN2, SRPK2, SRPK1, BAG3, PRPF38A, NKAP, ISY1, PRPF40A, ZCCHC10, RBMX2, SAP30BP, CHERP, RBM7, THOC1, MFAP1, DHX8, NOTCH1, KANSL1, PHF5A, MYPN, POLR1B, CRNKL1, TAF9, SMAD3, SMAD2, CAND1, CUL3, SIRT7, USP12,
Protein Size: 1220

Poids moléculaire: 139 kDa

ID gène: 1659

NCBI Accession: NM_004941, NP_004932

UniProt: Q14562