DHX8 anticorps (N-Term)
Aperçu rapide pour DHX8 anticorps (N-Term) (ABIN2775203)
Antigène
Voir toutes DHX8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- DHX8 Antibody - N-terminal region
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Séquence
- VKNGAEFTDS LISNLLRLIQ TMRPPAKPST SKDPVVKPKT EKEKLKELFP
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Homologie
- Cow: 100%, Dog: 88%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against DHX8. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human DHX8
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36380-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- DHX8 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 8 (DHX8))
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Autre désignation
- DHX8
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Sujet
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Background Information: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is highly homologous to yeast Prp22. This protein facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.
Gene Name: DEAH (Asp-Glu-Ala-His) box polypeptide 8
Alternative Symbols: DDX8, Dhr2, HRH1, PRP22, PRPF22
Protein Name: ATP-dependent RNA helicase DHX8
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Poids moléculaire
- 139kDa
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ID gène
- 1659
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NCBI Accession
- NP_004932
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UniProt
- Q14562
Antigène
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