INTS6 anticorps (C-Term)

N° du produit ABIN2775213

Cet anticorps Lapin Polyclonal détecte spécifiquement INTS6 dans WB. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Lapin et Chien.

Aperçu rapide pour INTS6 anticorps (C-Term) (ABIN2775213)

Antigène: INTS6 (Integrator Complex Subunit 6 (INTS6))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INTS6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-INTS6 anticorps

Épitope: C-Term

Séquence: GFLENHEEPR DKEQCAEENI PASSLNKGKK LMHCRSHEEV NTELKAQIMK

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against INTS6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human INTS6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 874 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur INTS6

Antigène: INTS6 (Integrator Complex Subunit 6 (INTS6))

Autre désignation: INTS6

Sujet: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. INTS6 is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: DBI-1, DDX26, DDX26A, DICE1, DKFZP434B105, HDB, INT6, Notchl2
Protein Interaction Partner: RPA3, RPA2, RPA1, BMI1, UBC, MCM7, INTS10, CTDP1, SHFM1, DDX26B, NAIF1, INTS4, VWA9, INTS5, NABP2, C7orf26, INTS3, ZNF687, INTS2, INTS12, INTS9, ASUN, INTS8, CPSF3L, INTS6, INTS1, INTS7, ZMYND8, ZNF592, PPP2R1B, PPP2R1A, PPP2CB, PPP2CA, PPP1CB, POLR2L, PO
Protein Size: 874

Poids moléculaire: 99 kDa

ID gène: 26512

NCBI Accession: NM_001039937, NP_001035026

UniProt: A8MV98