INTS6 anticorps (C-Term)

N° du produit ABIN2775213

Détail du produit anti-INTS6 anticorps

Antigène: INTS6 (Integrator Complex Subunit 6 (INTS6))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INTS6 est non-conjugé

Application: Western Blotting (WB)

Séquence: GFLENHEEPR DKEQCAEENI PASSLNKGKK LMHCRSHEEV NTELKAQIMK

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against INTS6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human INTS6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 874 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur INTS6

Antigène: INTS6 (Integrator Complex Subunit 6 (INTS6))

Autre désignation: INTS6 (INTS6 Produits)

Synonymes: anticorps DBI-1, anticorps DDX26, anticorps DDX26A, anticorps DICE1, anticorps HDB, anticorps INT6, anticorps Notchl2, anticorps EIF3-P48, anticorps EIF3S6, anticorps eIF3-p46, anticorps 2900075H24Rik, anticorps AI480962, anticorps Ddx26, anticorps Notch2l, anticorps LRRGT00024, anticorps ints6, anticorps zgc:63527, anticorps INTS6, anticorps ints6-b, anticorps Int6-A, anticorps dbi-1, anticorps ddx26, anticorps ddx26a, anticorps dice1, anticorps hdb, anticorps int6, anticorps ints6-a, anticorps notchl2, anticorps integrator complex subunit 6, anticorps eukaryotic translation initiation factor 3 subunit E, anticorps integrator complex subunit 6 like, anticorps integrator complex subunit 6 S homeolog, anticorps integrator complex subunit 6 L homeolog, anticorps INTS6, anticorps EIF3E, anticorps Ints6, anticorps ints6l, anticorps ints6, anticorps ints6.S, anticorps Tsp_09465, anticorps LOC100164318, anticorps ints6.L

Sujet: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. INTS6 is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: DBI-1, DDX26, DDX26A, DICE1, DKFZP434B105, HDB, INT6, Notchl2
Protein Interaction Partner: RPA3, RPA2, RPA1, BMI1, UBC, MCM7, INTS10, CTDP1, SHFM1, DDX26B, NAIF1, INTS4, VWA9, INTS5, NABP2, C7orf26, INTS3, ZNF687, INTS2, INTS12, INTS9, ASUN, INTS8, CPSF3L, INTS6, INTS1, INTS7, ZMYND8, ZNF592, PPP2R1B, PPP2R1A, PPP2CB, PPP2CA, PPP1CB, POLR2L, PO
Protein Size: 874

Poids moléculaire: 99 kDa

ID gène: 26512

NCBI Accession: NM_001039937, NP_001035026

UniProt: A8MV98