EIF4A3 anticorps (Middle Region)
Aperçu rapide pour EIF4A3 anticorps (Middle Region) (ABIN2775226)
Antigène
Voir toutes EIF4A3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- QCHACIGGTN VGEDIRKLDY GQHVVAGTPG RVFDMIRRRS LRTRAIKMLV
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against DDX48. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human DDX48
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 411 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- EIF4A3 (Eukaryotic Translation Initiation Factor 4A3 (EIF4A3))
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Autre désignation
- DDX48
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Sujet
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DDX48 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.
Alias Symbols: DDX48, NUK34, NMP265, eIF4AIII
Protein Interaction Partner: CDCA7L, PDCD4, HUWE1, POLDIP3, HAUS1, SUMO2, SUMO3, STAU1, UBC, LIN28B, SUMO1, WWOX, EED, RNF2, BMI1, SUZ12, ANP32A, PKM, NPLOC4, IPO11, PDLIM5, PLIN3, SRP14, RAD23B, AARS, FBXO6, SRPK2, SRPK1, UPF1, SMG1, RBM8A, ITGA4, CWC22, EEF2K, VCAM1, FN1, TRA2B, HN
Protein Size: 411 -
Poids moléculaire
- 45 kDa
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ID gène
- 9775
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NCBI Accession
- NM_014740, NP_055555
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UniProt
- P38919
Antigène
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