DDX50 anticorps (N-Term)

N° du produit ABIN2775257

Cet anticorps Lapin Polyclonal détecte spécifiquement DDX50 dans WB. Il présente une réactivité envers Humain, Chien, Boeuf (Vache), Cobaye, Cheval, Porc et Lapin et a été mentionné dans 1 publication.

Aperçu rapide pour DDX50 anticorps (N-Term) (ABIN2775257)

Antigène: DDX50 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 50 (DDX50))

Reactivité: Humain, Chien, Boeuf (Vache), Cobaye, Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDX50 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DDX50 anticorps

Épitope: N-Term

Séquence: EESESQKKER QKSDRRKSRH HYDSDEKSET RENGVTDDLD APKAKKSKMK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Pig: 93%, Rabbit: 100%

Attributs du produit: This is a rabbit polyclonal antibody against DDX50. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DDX50

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 737 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-DDX50 (ABIN2775257)

Valdez, Yang, Hong, Sequitin: "Genomic structure of newly identified paralogue of RNA helicase II/Gu: detection of pseudogenes and multiple alternatively spliced mRNAs." dans: Gene, Vol. 284, Issue 1-2, pp. 53-61, (2002) (PubMed).

Détails sur DDX50

Antigène: DDX50 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 50 (DDX50))

Autre désignation: DDX50

Sujet: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX50 is a DEAD box enzyme that may be involved in ribosomal RNA synthesis or processing. DDX50 and DDX21, also called RH-II/GuA, have similar genomic structures and are in tandem orientation on chromosome 10, suggesting that the two genes arose by gene duplication in evolution. DDX50 gene has pseudogenes on chromosomes 2, 3 and 4. Alternative splicing of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined.
Alias Symbols: GU2, GUB, RH-II/GuB
Protein Interaction Partner: SUMO3, UBC, LIN28A, PRKRA, TARBP2, EED, RNF2, TARDBP, SRPK2, WHSC1, KRAS, ESR1, BARD1, CAND1, CUL3, HDGF, STAU1, SRRM2,
Protein Size: 737

Poids moléculaire: 81 kDa

ID gène: 79009

NCBI Accession: NM_024045, NP_076950

UniProt: Q9BQ39