DHX58 anticorps (N-Term)

N° du produit ABIN2775259

Cet anticorps Lapin Polyclonal détecte spécifiquement DHX58 dans WB. Il présente une réactivité envers Humain, Rat, Souris, Cobaye, Cheval, Boeuf (Vache), Chien et Lapin.

Aperçu rapide pour DHX58 anticorps (N-Term) (ABIN2775259)

Antigène: DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

Reactivité: Humain, Rat, Souris, Cobaye, Cheval, Boeuf (Vache), Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DHX58 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DHX58 anticorps

Épitope: N-Term

Séquence: AYVAKRHLET VDGAKVVVLV NRVHLVTQHG EEFRRMLDGR WTVTTLSGDM

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 91%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against DHX58. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DHX58

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 678 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DHX58

Antigène: DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

Autre désignation: DHX58

Sujet: DHX58 is the negative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58-mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA. Bin
Alias Symbols: D11LGP2, D11lgp2e, LGP2
Protein Interaction Partner: USP21, APP, UBD, NKRF, CDKN2AIP, AGO2, STAU2, DICER1, DHX30, XRN2, STAU1, EIF2AK2, EIF6, AP2B1,
Protein Size: 678

Poids moléculaire: 76 kDa

ID gène: 79132

NCBI Accession: NM_024119, NP_077024

UniProt: Q96C10