DNA Helicase B anticorps (N-Term)
Aperçu rapide pour DNA Helicase B anticorps (N-Term) (ABIN2775262)
Antigène
Voir toutes DNA Helicase B (HELB) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- FGRFPITGAW WRVKVQVKPV VGSRSYQYQV QGFPSYFLQS DMSPPNQKHI
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Homologie
- Cow: 86%, Guinea Pig: 79%, Human: 100%, Pig: 86%, Rat: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against HELB. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Protein A purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human HELB
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 1087 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "A dominant-negative mutant of human DNA helicase B blocks the onset of chromosomal DNA replication." dans: The Journal of biological chemistry, Vol. 277, Issue 43, pp. 40853-61, (2002) (PubMed).
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: "A dominant-negative mutant of human DNA helicase B blocks the onset of chromosomal DNA replication." dans: The Journal of biological chemistry, Vol. 277, Issue 43, pp. 40853-61, (2002) (PubMed).
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- DNA Helicase B (HELB)
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Autre désignation
- HELB
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Sujet
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The protein encoded by this gene is a DNA helicase. A dominant-negative mutant of this protein blocks chromosomal DNA replication and suggests that its function is required for S phase entry.
Alias Symbols: hDHB
Protein Interaction Partner: UBC, PMS1, POLA2, POLA1, RPA1,
Protein Size: 1087 -
Poids moléculaire
- 120 kDa
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ID gène
- 92797
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NCBI Accession
- NM_033647, NP_387467
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UniProt
- Q8NG08
Antigène
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