CES2 anticorps (C-Term)

N° du produit ABIN2775271

Il existe 1 publication pour ce produit. L’anticorps anti-CES2 Polyclonal Lapin est utilisé pour la détection de CES2 dans des échantillons de Humain, Souris, Rat, Chien et Cobaye. Il a été validé pour WB et IHC.

Aperçu rapide pour CES2 anticorps (C-Term) (ABIN2775271)

Antigène: CES2 (Carboxylesterase 2 (CES2))

Reactivité: Humain, Souris, Rat, Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CES2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-CES2 anticorps

Épitope: C-Term

Fonction: CES2 Antibody - C-terminal region

Séquence: HWPLFDQEEQ YLQLNLQPAV GRALKAHRLQ FWKKALPQKI QELEEPEERH

Homologie: Dog: 83%, Guinea Pig: 83%, Human: 100%, Mouse: 83%, Rat: 83%

Attributs du produit: This is a rabbit polyclonal antibody against CES2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CES2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8096212

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CES2 (ABIN2775271)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." dans: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Détails sur CES2

Antigène: CES2 (Carboxylesterase 2 (CES2))

Autre désignation: CES2

Sujet:

Background Information: Carboxylesterase 2 is a member of a large multigene family. The enzymes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined, however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system.Carboxylesterase 2 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined, however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Name: Carboxylesterase 2

Alternative Symbols: iCE, CE-2, PCE-2, CES2A1

Protein Name: Cocaine esterase

Poids moléculaire: 69kDa

ID gène: 8824

NCBI Accession: NP_003860

UniProt: O00748