NNMT anticorps (N-Term)

N° du produit ABIN2775335

Il existe 1 publication pour ce produit. L’anticorps anti-NNMT Polyclonal Lapin est utilisé pour la détection de NNMT dans des échantillons de Humain, Souris, Rat, Chien et Porc. Il a été validé pour WB.

Aperçu rapide pour NNMT anticorps (N-Term) (ABIN2775335)

Antigène: NNMT (Nicotinamide N-Methyltransferase (NNMT))

Reactivité: Humain, Souris, Rat, Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NNMT est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NNMT anticorps

Épitope: N-Term

Fonction: NNMT Antibody - N-terminal region

Séquence: MESGFTSKDT YLSHFNPRDY LEKYYKFGSR HSAESQILKH LLKNLFKIFC

Homologie: Dog: 93%, Human: 100%, Mouse: 100%, Pig: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against NNMT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NNMT

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42281-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-NNMT (ABIN2775335)

Ulanovskaya, Zuhl, Cravatt: "NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink." dans: Nature chemical biology, Vol. 9, Issue 5, pp. 300-6, (2013) (PubMed).

Détails sur NNMT

Antigène: NNMT (Nicotinamide N-Methyltransferase (NNMT))

Autre désignation: NNMT

Sujet:

Background Information: N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. NNMT responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.

Gene Name: Nicotinamide N-methyltransferase

Protein Name: Nicotinamide N-methyltransferase

Poids moléculaire: 29kDa

ID gène: 4837

NCBI Accession: NP_006160

UniProt: P40261