GREM1 anticorps (C-Term)

N° du produit ABIN2775383

Cet anticorps anti-GREM1 Polyclonal Lapin (ABIN2775383) détecte spécifiquement GREM1 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Chévre, Cobaye, Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour GREM1 anticorps (C-Term) (ABIN2775383)

Antigène: GREM1 (Gremlin 1 (GREM1))

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Chévre, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GREM1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GREM1 anticorps

Épitope: C-Term

Séquence: EEGSFQSCSF CKPKKFTTMM VTLNCPELQP PTKKKRVTRV KQCRCISIDL

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against Grem1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Grem1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 184 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GREM1

Antigène: GREM1 (Gremlin 1 (GREM1))

Autre désignation: Grem1

Sujet: Grem1 is a cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis, as BMP a antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop. It down-regulates the BMP4 signaling in a dose-dependent manner and acts as inhibitor of monocyte chemotaxis.
Alias Symbols: Cktsf1b1, Drm, ld
Protein Size: 184

Poids moléculaire: 21 kDa

ID gène: 23892

NCBI Accession: NM_011824, NP_035954

UniProt: O70326

Pathways: Regulation of Muscle Cell Differentiation, Tube Formation, Maintenance of Protein Location