nectin-3 anticorps (N-Term)
Aperçu rapide pour nectin-3 anticorps (N-Term) (ABIN2775419)
Antigène
Voir toutes nectin-3 (NECTIN3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- NECTIN3 Antibody - N-terminal region
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Séquence
- SGKYICKAVT FPLGNAQSST TVTVLVEPTV SLIKGPDSLI DGGNETVAAI
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against PVRL3. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human PVRL3
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42446-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
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Autre désignation
- NECTIN3
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Sujet
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Background Information: This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants.
Gene Name: nectin cell adhesion molecule 3
Alternative Symbols: PPR3, PRR3, CD113, PVRL3, PVRR3, CDW113, NECTIN-3
Protein Name: nectin-3
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Poids moléculaire
- 61kDa
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ID gène
- 25945
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NCBI Accession
- NP_056295
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UniProt
- Q9NQS3
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Pathways
- Cell-Cell Junction Organization
Antigène
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