nectin-3 anticorps (Middle Region)

N° du produit ABIN785184

Détail du produit anti-nectin-3 anticorps

Antigène: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp nectin-3 est non-conjugé

Application: Western Blotting (WB)

Séquence: PDSVKKENKN PVNNLIRKDY LEEPEKTQWN NVENLNRFER PMDYYEDLKM

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PVRL3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PVRL3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 549 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur nectin-3

Antigène: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Autre désignation: PVRL3 (NECTIN3 Produits)

Synonymes: anticorps PVRL3, anticorps CD113, anticorps CDW113, anticorps NECTIN-3, anticorps PPR3, anticorps PRR3, anticorps PVRR3, anticorps 2610301B19Rik, anticorps 3000002N23Rik, anticorps 4921513D19Rik, anticorps AA407785, anticorps AU016832, anticorps AW538082, anticorps nectin cell adhesion molecule 3, anticorps poliovirus receptor-related 3, anticorps Nectin3, anticorps NECTIN3, anticorps PVRL3, anticorps nectin3

Sujet: Nectins (e.g., PVRL1, MIM 600644) are immunoglobulin-like adhesion molecules that interact with afadin (AF6, MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin (see MIM 192090)-catenin (see MIM 116805) system in epithelial cells.
Alias Symbols: CDw113, DKFZP566B0846, FLJ90624, PPR3, PRR3, PVRR3, nectin-3, CD113, CDW113, NECTIN-3
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, KRTAP10-8, KRTAP10-9, KRTAP10-7, KRTAP4-2, RGS20, UBC, BAG3, TIGIT, PVRL2, PVRL1, PARD3, PVR, MLLT4, PVRL3,
Protein Size: 549

Poids moléculaire: 61 kDa

ID gène: 25945

NCBI Accession: NM_015480, NP_056295

UniProt: Q9NQS3

Pathways: Cell-Cell Junction Organization