UPB1 anticorps (Middle Region)

N° du produit ABIN2775431

Cet anticorps anti-UPB1 est un anticorps Lapin Polyclonal détectant UPB1 dans WB. Adapté pour Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Cheval, Lapin, Boeuf (Vache), Cobaye et Chévre. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour UPB1 anticorps (Middle Region) (ABIN2775431)

Antigène: UPB1 (Ureidopropionase, beta (UPB1))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Cheval, Lapin, Boeuf (Vache), Cobaye, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UPB1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-UPB1 anticorps

Épitope: Middle Region

Séquence: AVVISNSGAV LGKTRKNHIP RVGDFNESTY YMEGNLGHPV FQTQFGRIAV

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against UPB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human UPB1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 384 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-UPB1 (ABIN2775431)

Kunicka, Prochazka, Krus, Bendova, Protivova, Susova, Hlavac, Liska, Novak, Schneiderova, Pitule, Bruha, Vycital, Vodicka, Soucek: "Molecular profile of 5-fluorouracil pathway genes in colorectal carcinoma." dans: BMC cancer, Vol. 16, Issue 1, pp. 795, (2016) (PubMed).

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." dans: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Détails sur UPB1

Antigène: UPB1 (Ureidopropionase, beta (UPB1))

Autre désignation: UPB1

Sujet: UPB1 is a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activityThis gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.
Alias Symbols: BUP1
Protein Size: 384

Poids moléculaire: 42 kDa

ID gène: 51733

NCBI Accession: NM_016327, NP_057411

UniProt: Q9UBR1