HAO1 anticorps (C-Term)
Aperçu rapide pour HAO1 anticorps (C-Term) (ABIN2775438)
Antigène
Voir toutes HAO1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- GLNGILVSNH GARQLDGVPA TIDVLPEIVE AVEGKVEVFL DGGVRKGTDV
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against HAO1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human HAO1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 370 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Identification and expression of a cDNA for human glycolate oxidase." dans: Biochimica et biophysica acta, Vol. 1493, Issue 1-2, pp. 246-8, (2000) (PubMed).
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: "Identification and expression of a cDNA for human glycolate oxidase." dans: Biochimica et biophysica acta, Vol. 1493, Issue 1-2, pp. 246-8, (2000) (PubMed).
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- HAO1 (Hydroxyacid Oxidase (Glycolate Oxidase) 1 (HAO1))
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Autre désignation
- HAO1
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Sujet
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Subcellular location of HAO1 is the peroxisome. Specifically, HAO1 is expressed primarily in liver and pancreas and is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids.This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site.
Alias Symbols: GOX, GOX1, HAOX1
Protein Interaction Partner: PEX5, HCVgp1,
Protein Size: 370 -
Poids moléculaire
- 41 kDa
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ID gène
- 54363
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NCBI Accession
- NM_017545, NP_060015
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UniProt
- Q9UJM8
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Pathways
- Monocarboxylic Acid Catabolic Process
Antigène
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