ANO1 anticorps (Middle Region)

N° du produit ABIN2775453

Détail du produit anti-ANO1 anticorps

Antigène: ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANO1 est non-conjugé

Application: Western Blotting (WB)

Séquence: HGFVNHTLSS FNVSDFQNGT APNDPLDLGY EVQICRYKDY REPPWSENKY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TMEM16A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TMEM16A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 960 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ANO1 (ABIN2775453)

Liu, Zhang, Huang, Qi, Xu, Gao, Du, Gamper, Zhang: "Characterization of the effects of Cl⁻ channel modulators on TMEM16A and bestrophin-1 Ca²⁺ activated Cl⁻ channels." dans: Pflügers Archiv : European journal of physiology, Vol. 467, Issue 7, pp. 1417-1430, (2015) (PubMed).

Banga, Flaig, Lewis, Winfree, Blazer-Yost: "Epinephrine stimulation of anion secretion in the Calu-3 serous cell model." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 306, Issue 10, pp. L937-46, (2014) (PubMed).

Détails sur ANO1

Antigène: ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))

Autre désignation: TMEM16A (ANO1 Produits)

Synonymes: anticorps DOG1, anticorps ORAOV2, anticorps TAOS2, anticorps TMEM16A, anticorps Tmem16a, anticorps anoctamin 1, anticorps anoctamin 1, calcium activated chloride channel, anticorps Ano1, anticorps ANO1

Sujet: TMEM16A belongs to the anoctamin family. TMEM16A acts as a calcium-activated chloride channel. It is required for normal tracheal development.
Alias Symbols: FLJ10261, ORAOV2, TAOS2, CACC, DOG1, TMEM16A, ANO1
Protein Interaction Partner: UBC,
Protein Size: 960

Poids moléculaire: 111 kDa

ID gène: 55107

NCBI Accession: NM_018043, NP_060513

UniProt: Q5XXA6