PARD6A anticorps (N-Term)

N° du produit ABIN2775615

Cet anticorps anti-PARD6A Polyclonal Lapin (ABIN2775615) détecte spécifiquement PARD6A dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Cobaye et Chien.

Aperçu rapide pour PARD6A anticorps (N-Term) (ABIN2775615)

Antigène: PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Cobaye, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARD6A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PARD6A anticorps

Épitope: N-Term

Fonction: PARD6A Antibody - N-terminal region

Séquence: MARPQRTPAR SPDSIVEVKS KFDAEFRRFA LPRASVSGFQ EFSRLLRAVH

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PARD6A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PARD6A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42883-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PARD6A

Antigène: PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))

Autre désignation: PARD6A

Sujet:

Background Information: This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Name: Par-6 partitioning defective 6 homolog alpha (C. elegans)

Alternative Symbols: PAR6, PAR6C, TAX40, PAR-6A, TIP-40, PAR6alpha

Protein Name: Putative uncharacterized protein EMBL BAE34693.1

Poids moléculaire: 37kDa

ID gène: 50855

NCBI Accession: NP_001032358

UniProt: Q3TY70

Pathways: Cell-Cell Junction Organization