Occludin anticorps (N-Term)

N° du produit ABIN2775620

Il existe 1 publication pour ce produit. L’anticorps anti-Occludin Polyclonal Lapin est utilisé pour la détection de Occludin dans des échantillons de Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Boeuf (Vache) et Poisson zèbre (Danio rerio). Il a été validé pour WB.

Aperçu rapide pour Occludin anticorps (N-Term) (ABIN2775620)

Antigène: Occludin (OCLN)

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Occludin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Occludin anticorps

Épitope: N-Term

Fonction: OCLN Antibody - N-terminal region

Séquence: VRPMLSQPAY SFYPEDEILH FYKWTSPPGV IRILSMLIIV MCIAIFACVA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%

Attributs du produit: This is a rabbit polyclonal antibody against OCLN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human OCLN

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42889-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Occludin (ABIN2775620)

Yang, Liu, Miao, Yang, Fu, Dou, Cai, Zong, Tan, Chen, Wang: "Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier." dans: Oncotarget, Vol. 7, Issue 39, pp. 63839-63855, (2016) (PubMed).

Détails sur Occludin

Antigène: Occludin (OCLN)

Autre désignation: OCLN

Sujet:

Background Information: OCLN is an integral membrane protein which is located at tight junctions. This protein may be involved in the formation and maintenance of the tight junction. The possibility of several alternatively spliced products has been suggested but the full nature of these products has not been described. This gene encodes an integral membrane protein which is located at tight junctions. This protein may be involved in the formation and maintenance of the tight junction. The possibility of several alternatively spliced products has been suggested but the full nature of these products has not been described. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Gene Name: Occludin

Alternative Symbols: BLCPMG

Protein Name: Occludin

Poids moléculaire: 59kDa

ID gène: 4950

NCBI Accession: NP_002529

UniProt: Q16625

Pathways: Cell-Cell Junction Organization, Hepatitis C