PARD6B anticorps (N-Term)
Aperçu rapide pour PARD6B anticorps (N-Term) (ABIN2775630)
Antigène
Voir toutes PARD6B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- SKFGAEFRRF SLERSKPGKF EEFYGLLQHV HKIPNVDVLV GYADIHGDLL
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Homologie
- Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%, Zebrafish: 85%
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Attributs du produit
- This is a rabbit polyclonal antibody against Pard6b. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of MOUSE Pard6b
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PARD6B (Par-6 Partitioning Defective 6 Homolog beta (PARD6B))
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Autre désignation
- Pard6b
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Sujet
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Pard6b is a adapter protein involved in asymmetrical cell division and cell polarization processes. It is probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Alias Symbols: AV025615, Par6b
Protein Interaction Partner: Llgl1,
Protein Size: 371 -
Poids moléculaire
- 40 kDa
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ID gène
- 58220
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NCBI Accession
- NM_021409, NP_067384
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UniProt
- Q9JK83
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Pathways
- Cell-Cell Junction Organization
Antigène
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