AMOTL1 anticorps (N-Term)

N° du produit ABIN2775636

Il existe 2+ publications pour ce produit. L’anticorps anti-AMOTL1 Polyclonal Lapin est utilisé pour la détection de AMOTL1 dans des échantillons de Humain, Souris, Boeuf (Vache), Chien, Cobaye et Lapin. Il a été validé pour WB.

Aperçu rapide pour AMOTL1 anticorps (N-Term) (ABIN2775636)

Antigène: AMOTL1 (Angiomotin Like 1 (AMOTL1))

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AMOTL1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-AMOTL1 anticorps

Épitope: N-Term

Fonction: AMOTL1 Antibody - N-terminal region

Séquence: LTQEDPQMVY QSARQEPQGQ EHQVDNTVME KQVRSTQPQQ NNEELPTYEE

Homologie: Cow: 93%, Dog: 79%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%

Attributs du produit: This is a rabbit polyclonal antibody against AMOTL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human AMOTL1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42927-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-AMOTL1 (ABIN2775636)

Skouloudaki, Walz: "YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation." dans: PLoS ONE, Vol. 7, Issue 4, pp. e35735, (2012) (PubMed).

Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." dans: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

Détails sur AMOTL1

Antigène: AMOTL1 (Angiomotin Like 1 (AMOTL1))

Autre désignation: AMOTL1

Sujet:

Background Information: AMOTL1 is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.

Gene Name: Angiomotin like 1

Alternative Symbols: JEAP

Protein Name: Angiomotin-like protein 1

Poids moléculaire: 107 kDa

ID gène: 154810

NCBI Accession: NP_570899

UniProt: Q8IY63