PATJ anticorps (N-Term)
Aperçu rapide pour PATJ anticorps (N-Term) (ABIN2775641)
Antigène
Voir toutes PATJ (INADL) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- PATJ Antibody - N-terminal region
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Séquence
- EVMVATLDTQ IADDAELQKY SKLLPIHTLR LGVEVDSFDG HHYISSIVSG
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against INADL. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human INADL
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42938-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "PATJ, a tight junction-associated PDZ protein, is a novel degradation target of high-risk human papillomavirus E6 and the alternatively spliced isoform 18 E6." dans: Journal of virology, Vol. 81, Issue 8, pp. 4080-90, (2007) (PubMed).
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- PATJ (INADL) (InaD-Like (INADL))
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Autre désignation
- PATJ
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Sujet
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Background Information: This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors.
Gene Name: PATJ, crumbs cell polarity complex component
Alternative Symbols: Cipp, INADL, hINADL, InaD-like
Protein Name: inaD-like protein
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Poids moléculaire
- 196kDa
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ID gène
- 10207
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NCBI Accession
- NP_795352
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UniProt
- Q8NI35
Antigène
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