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UBE2D2 anticorps (N-Term)

UBE2D2 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio), Cheval, Cobaye, Chévre WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2775672
  • Antigène Voir toutes UBE2D2 Anticorps
    UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
    Épitope
    • 15
    • 12
    • 9
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 59
    • 30
    • 14
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio), Cheval, Cobaye, Chévre
    Hôte
    • 52
    • 7
    Lapin
    Clonalité
    • 53
    • 6
    Polyclonal
    Conjugué
    • 31
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp UBE2D2 est non-conjugé
    Application
    • 53
    • 27
    • 13
    • 13
    • 9
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    ALKRIHKELN DLARDPPAQC SAGPVGDDMF HWQATIMGPN DSPYQGGVFF
    Homologie
    Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against UBE2D2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2D2
    Top Product
    Discover our top product UBE2D2 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 147 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))
    Autre désignation
    UBE2D2 (UBE2D2 Produits)
    Synonymes
    anticorps E2(17)KB2, anticorps PUBC1, anticorps UBC4, anticorps UBC4/5, anticorps UBCH5B, anticorps 1500034D03Rik, anticorps Ubc2e, anticorps Ube2d2, anticorps ubc4, anticorps ube2d2, anticorps zgc:55886, anticorps E217kB, anticorps ubiquitin conjugating enzyme E2 D2, anticorps ubiquitin-conjugating enzyme E2D 2A, anticorps ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), anticorps ubiquitin-conjugating enzyme E2D 2, anticorps ubiquitin conjugating enzyme E2 D3, anticorps UBE2D2, anticorps Ube2d2a, anticorps ube2d2, anticorps Ube2d2, anticorps UBE2D3
    Sujet
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D2 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
    Alias Symbols: E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH5B
    Protein Interaction Partner: RNF26, CHFR, RBX1, DZIP3, UBA1, UBC, TRAF6, BIRC7, anapc11, ZNRF1, RNF146, MID1, MDM2, BIRC3, FZR1, ITCH, HRD1, CUL3, XIAP, MARCH7, RNF25, UBE2D2, RNF130, UBA6, CBLC, PARK2, TRIM21, KCMF1, RNF135, MUL1, MDM4, TRIM23, STUB1, CBL, UBTD1, RNF38, UBI4, RFFL,
    Protein Size: 147
    Poids moléculaire
    17 kDa
    ID gène
    7322
    NCBI Accession
    NM_003339, NP_003330
    UniProt
    P62837
    Pathways
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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