UBE2D2 anticorps (Middle Region)

N° du produit ABIN2775673

Cet anticorps anti-UBE2D2 est un anticorps Lapin Polyclonal détectant UBE2D2 dans WB et IHC. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio), Cheval et Cobaye. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour UBE2D2 anticorps (Middle Region) (ABIN2775673)

Antigène: UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Poisson zèbre (Danio rerio), Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2D2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-UBE2D2 anticorps

Épitope: Middle Region

Séquence: SQWSPALTIS KVLLSICSLL CDPNPDDPLV PEIARIYKTD REKYNRIARE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against UBE2D2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human UBE2D2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 547 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-UBE2D2 (ABIN2775673)

Desforges, Lacey, Glazier, Greenwood, Mynett, Speake, Sibley: "SNAT4 isoform of system A amino acid transporter is expressed in human placenta." dans: American journal of physiology. Cell physiology, Vol. 290, Issue 1, pp. C305-12, (2005) (PubMed).

Détails sur UBE2D2

Antigène: UBE2D2 (Ubiquitin-Conjugating Enzyme E2D 2 (UBE2D2))

Autre désignation: UBE2D2

Sujet: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D2 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.SLC38A4 is found predominantly in liver and transports both cationic and neutral amino acids. The transport of cationic amino acids by SLC38A4 is Na(+) and pH independent, while the transport of neutral amino acids is Na(+) and pH dependent (Hatanaka et al., 2001).[supplied by OMIM].
Alias Symbols: E2(17)KB2, PUBC1, UBC4, UBC4/5, UBCH5B
Protein Interaction Partner: RNF26, CHFR, RBX1, DZIP3, UBA1, UBC, TRAF6, BIRC7, anapc11, ZNRF1, RNF146, MID1, MDM2, BIRC3, FZR1, ITCH, HRD1, CUL3, XIAP, MARCH7, RNF25, UBE2D2, RNF130, UBA6, CBLC, PARK2, TRIM21, KCMF1, RNF135, MUL1, MDM4, TRIM23, STUB1, CBL, UBTD1, RNF38, UBI4, RFFL,
Protein Size: 547

Poids moléculaire: 60 kDa

ID gène: 7322

NCBI Accession: NM_018018, NP_003330

UniProt: P62837

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades