UBE2L3 anticorps (Middle Region)

N° du produit ABIN2775682

Détail du produit anti-UBE2L3 anticorps

Antigène: UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2L3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: WQGLIVPDNP PYDKGAFRIE INFPAEYPFK PPKITFKTKI YHPNIDEKGQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against UBE2L3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human UBE2L3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 154 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur UBE2L3

Antigène: UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))

Autre désignation: UBE2L3 (UBE2L3 Produits)

Synonymes: anticorps E2-F1, anticorps L-UBC, anticorps UBCH7, anticorps UbcM4, anticorps C79827, anticorps Ubce7, anticorps ube2l3, anticorps wu:fc22h11, anticorps zgc:86727, anticorps UBE2L3, anticorps ube2l3l, anticorps wu:fb38h03, anticorps ubiquitin conjugating enzyme E2 L3, anticorps ubiquitin-conjugating enzyme E2L 3, anticorps ubiquitin-conjugating enzyme E2L 3a, anticorps ubiquitin conjugating enzyme E2 L3 S homeolog, anticorps ubiquitin-conjugating enzyme E2L 3b, anticorps UBE2L3, anticorps Ube2l3, anticorps ube2l3a, anticorps ube2l3.S, anticorps ube2l3b

Sujet: UBE2L3 catalyzes the covalent attachment of ubiquitin to other proteins.It mediates the selective degradation of short-lived and abnormal proteins. UBE2L3 functions in the E6/E6-AP-induced ubiquitination of p53/TP53.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: E2-F1, L-UBC, UBCH7, UbcM4
Protein Interaction Partner: UBC, TRAF6, NEDD4, ITCH, MUL1, SMURF2, SMURF1, WWP2, WWP1, ARIH2, RNF144A, UBA1, PARK2, RNF144B, HACE1, ARIH1, UBE3A, UBE2L3, UBA6, UBR5, CACNA1B, MAP1LC3B, BAG3, HSPA4, AICDA, CCNB1IP1, FN1, RBX1, LIG4, ZPR1, USP9X, SF1, VDAC2, UCHL3, UBE2V2, UBE2D2, UBE
Protein Size: 154

Poids moléculaire: 18 kDa

ID gène: 7332

NCBI Accession: NM_003347, NP_003338

UniProt: Q5R5I4