UBE2M anticorps (N-Term)

N° du produit ABIN2775686

Détail du produit anti-UBE2M anticorps

Antigène: UBE2M (ube2m) (Ubiquitin-Conjugating Enzyme E2M (ube2m))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2M est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: IKLFSLKQQK KEEESAGGTK GSSKKASAAQ LRIQKDINEL NLPKTCDISF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against UBE2M. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2M

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 183 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-UBE2M (ABIN2775686)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Détails sur UBE2M

Antigène: UBE2M (ube2m) (Ubiquitin-Conjugating Enzyme E2M (ube2m))

Autre désignation: UBE2M (ube2m Produits)

Synonymes: anticorps DDBDRAFT_0204633, anticorps DDBDRAFT_0238042, anticorps DDB_0204633, anticorps DDB_0238042, anticorps UBC-RS2, anticorps UBC12, anticorps hUbc12, anticorps 2510040H03Rik, anticorps Ubc-rs2, anticorps ubiquitin conjugating enzyme E2M, anticorps ubiquitin-conjugating enzyme E2M, anticorps ubiquitin conjugating enzyme E2 M, anticorps NEDD8-conjugating enzyme, anticorps ubiquitin conjugating enzyme E2M S homeolog, anticorps ube2m, anticorps LOC692934, anticorps UBE2M, anticorps Ube2m, anticorps ube2m.S

Sujet: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2M is a member of the E2 ubiquitin-conjugating enzyme family. It is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.
Alias Symbols: UBC-RS2, UBC12, hUbc12
Protein Interaction Partner: DCUN1D1, DCUN1D4, RBX1, UBC, MARCH7, UBE2M, CUL1, DCUN1D3, SMURF1, CAND1, DCUN1D2, NEDD8, DCUN1D5, LMNA, VCAM1, ITGA4, FN1, VCP, UBE2D2, TYMS, TST, VAMP2, PARK2, PINK1, UBE2T, SEC22B, SLC9A3R2, APP, CUL3, CUL4A, TP53, UBD, COPS6, UBA3, NAE1, CUL2, Nedd4,
Protein Size: 183

Poids moléculaire: 21 kDa

ID gène: 9040

NCBI Accession: NM_003969, NP_003960

UniProt: P61081