CDC23 anticorps (N-Term)

N° du produit ABIN2775690

Cet anticorps Lapin Polyclonal détecte spécifiquement CDC23 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour CDC23 anticorps (N-Term) (ABIN2775690)

Antigène: CDC23 (Cell Division Cycle 23 (CDC23))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC23 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CDC23 anticorps

Épitope: N-Term

Séquence: RAAHFLHGCN SKKAYFLYMY SRYLSGEKKK DDETVDSLGP LEKGQVKNEA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CDC23. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CDC23

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 597 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CDC23

Antigène: CDC23 (Cell Division Cycle 23 (CDC23))

Autre désignation: CDC23

Sujet: CDC23 shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
Alias Symbols: APC8, CUT23, ANAPC8
Protein Interaction Partner: CCDC36, DLX6-AS1, SPERT, KCTD6, FAM9B, CCDC24, SSX2IP, PNMA5, CRACR2A, LZTS2, ATRIP, INCA1, CEP44, SLC52A2, EIF5A2, BCAS3, CYB5R2, HEMK1, RSL24D1, RBM15B, ANAPC2, UBE2S, INPP5J, GORASP2, ANAPC13, RAD54B, RBPMS, OPTN, CDC23, APOL1, COIL, UBC, SOX5, SIAH1,
Protein Size: 597

Poids moléculaire: 66 kDa

ID gène: 8697

NCBI Accession: NM_004661, NP_004652

UniProt: Q9UJX2

Pathways: Protein targeting to Nucleus