CBX1 anticorps (N-Term)

N° du produit ABIN2775787

Cet anticorps anti-CBX1 est un anticorps Lapin Polyclonal détectant CBX1 dans WB. Adapté pour Humain, Souris, Rat, Chien, Porc, Boeuf (Vache), Cheval, Lapin, Saccharomyces cerevisiae et Poisson zèbre (Danio rerio). Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour CBX1 anticorps (N-Term) (ABIN2775787)

Antigène: CBX1 (Chromobox Homolog 1 (CBX1))

Reactivité: Humain, Souris, Rat, Chien, Porc, Boeuf (Vache), Cheval, Lapin, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBX1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CBX1 anticorps

Épitope: N-Term

Séquence: MGKKQNKKKV EEVLEEEEEE YVVEKVLDRR VVKGKVEYLL KWKGFSDEDN

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against CBX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CBX1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 185 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CBX1 (ABIN2775787)

Ayoub, Jeyasekharan, Bernal, Venkitaraman: "HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response." dans: Nature, Vol. 453, Issue 7195, pp. 682-6, (2008) (PubMed).

Détails sur CBX1

Antigène: CBX1 (Chromobox Homolog 1 (CBX1))

Autre désignation: CBX1

Sujet: CBX1 is the component of heterochromatin. CBX1 recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. CBX1 interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the in
Alias Symbols: CBX, HP1-BETA, HP1Hs-beta, M31, MOD1, p25beta, HP1Hsbeta
Protein Interaction Partner: PRDM6, SUMO1, UBC, RNF2, PARK2, NR2F6, VHL, EHMT2, ABI3BP, VTN, TRIM39, CBX5, HIST1H3B, KLF11, HIST3H3, PCNA, MECP2, ADNP, POGZ, ADNP2, CBX3, TRIM28, CHAF1A, HIST1H4F, XRCC6, CHD4, H2AFB1, NSL1, SUMO2, HIST1H3A, Mad2l2, Cbx1, DNMT3B, ZNF382, H3F3A, SUV420
Protein Size: 185

Poids moléculaire: 21 kDa

ID gène: 10951

NCBI Accession: NM_006807, NP_006798

UniProt: P83916