CBX1 anticorps (N-Term)
Aperçu rapide pour CBX1 anticorps (N-Term) (ABIN2775787)
Antigène
Voir toutes CBX1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- CBX1 Antibody - N-terminal region
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Séquence
- MGKKQNKKKV EEVLEEEEEE YVVEKVLDRR VVKGKVEYLL KWKGFSDEDN
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Homologie
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against CBX1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human CBX1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34426-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response." dans: Nature, Vol. 453, Issue 7195, pp. 682-6, (2008) (PubMed).
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- CBX1 (Chromobox Homolog 1 (CBX1))
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Autre désignation
- CBX1
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Sujet
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Background Information: CBX1 is the component of heterochromatin. CBX1 recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. CBX1 interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the in
Gene Name: Chromobox homolog 1
Alternative Symbols: CBX, M31, MOD1, p25beta, HP1-BETA, HP1Hsbeta, HP1Hs-beta
Protein Name: Chromobox protein homolog 1
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Poids moléculaire
- 21kDa
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ID gène
- 10951
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NCBI Accession
- NP_006798
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UniProt
- P83916
Antigène
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