CBX1 anticorps (Middle Region)
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- Antigène Voir toutes CBX1 Anticorps
- CBX1 (Chromobox Homolog 1 (CBX1))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Porc, Cheval, Lapin, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CBX1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- PDLIAEFLQS QKTAHETDKS EGGKRKADSD SEDKGEESKP KKKKEESEKP
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against CBX1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human CBX1
- Top Product
- Discover our top product CBX1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 185 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- CBX1 (Chromobox Homolog 1 (CBX1))
- Autre désignation
- CBX1 (CBX1 Produits)
- Synonymes
- anticorps CBX, anticorps HP1-BETA, anticorps HP1Hs-beta, anticorps HP1Hsbeta, anticorps M31, anticorps MOD1, anticorps p25beta, anticorps Cbx, anticorps Cbx-rs2, anticorps E430007M08Rik, anticorps HP1B, anticorps Hp1beta, anticorps cbx1, anticorps wu:fe14b09, anticorps zgc:55739, anticorps zgc:86924, anticorps chromobox 1, anticorps chromobox homolog 1a (HP1 beta homolog Drosophila), anticorps chromobox 1 S homeolog, anticorps chromobox homolog 1b (HP1 beta homolog Drosophila), anticorps CBX1, anticorps Cbx1, anticorps cbx1a, anticorps cbx1.S, anticorps cbx1b
- Sujet
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CBX1 is the component of heterochromatin. CBX1 recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. CBX1 interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.Heterochromatin protein-1 (HP1) is localized at heterochromatin sites, where it mediates gene silencing.[supplied by OMIM].
Alias Symbols: CBX, M31, MOD1, p25beta, HP1-BETA, HP1Hsbeta, HP1Hs-beta
Protein Interaction Partner: PRDM6, SUMO1, UBC, RNF2, PARK2, NR2F6, VHL, EHMT2, ABI3BP, VTN, TRIM39, CBX5, HIST1H3B, KLF11, HIST3H3, PCNA, MECP2, ADNP, POGZ, ADNP2, CBX3, TRIM28, CHAF1A, HIST1H4F, XRCC6, CHD4, H2AFB1, NSL1, SUMO2, HIST1H3A, Mad2l2, Cbx1, DNMT3B, ZNF382, H3F3A, SUV420
Protein Size: 185 - Poids moléculaire
- 21 kDa
- ID gène
- 10951
- NCBI Accession
- NM_006807, NP_006798
- UniProt
- P83916
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