RRN3 anticorps (Middle Region)

N° du produit ABIN2775808

Cet anticorps Lapin Polyclonal détecte spécifiquement RRN3 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Lapin, Cobaye, Boeuf (Vache), Chien et Cheval.

Aperçu rapide pour RRN3 anticorps (Middle Region) (ABIN2775808)

Antigène: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Reactivité: Humain, Souris, Rat, Lapin, Cobaye, Boeuf (Vache), Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RRN3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RRN3 anticorps

Épitope: Middle Region

Séquence: VDGKVDNGKT KDLYRDLINI FDKLLLPTHA SCHVQFFMFY LCSFKLGFAE

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RRN3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RRN3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 650 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RRN3

Antigène: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Autre désignation: RRN3

Sujet: In mammals, growth-dependent regulation of RNA polymerase I (Pol I) transcription is mediated by RRN3, an essential initiation factor. It interacts with Pol I in the absence of template DNA, augments Pol I transcription in vivo and rescues transcription in extracts from growth-arrested cells in vitro.
Alias Symbols: TIFIA, A-270G1.2
Protein Interaction Partner: UBC, ACTA1, Polr1e, POLR1B, EIF3L, NMI, RBM15, UBD, Trim28, ELAVL1, TAF1D, POLR1A, MYO1C, TAF1C, TAF1B, TAF1A, UBTF, TBP, PPP2R2A, CDK2, CCNE1, RIBIN, ACTB,
Protein Size: 650

Poids moléculaire: 74 kDa

ID gène: 54700

NCBI Accession: NM_018427, NP_060897

UniProt: Q9NYV6

Pathways: Negative Regulation of intrinsic apoptotic Signaling