MIER1 anticorps (Middle Region)

N° du produit ABIN2775813

Cet anticorps anti-MIER1 est un anticorps Lapin Polyclonal détectant MIER1 dans WB. Adapté pour Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Lapin, Cobaye et Cheval.

Aperçu rapide pour MIER1 anticorps (Middle Region) (ABIN2775813)

Antigène: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Lapin, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MIER1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MIER1 anticorps

Épitope: Middle Region

Séquence: RRTGDEKGVE AIPEGSHIKD NEQALYELVK CNFDTEEALR RLRF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MIER1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MIER1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 536 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MIER1

Antigène: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Autre désignation: MIER1

Sujet: The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).
Alias Symbols: ER1, MI-ER1, hMI-ER1, RP5-944N15.1
Protein Interaction Partner: TMEM171, SOX2, HDAC2, HDAC1, EHMT2, CDYL, TUBB1, APP, ELAVL1, UBC, CREBBP, SP1,
Protein Size: 536

Poids moléculaire: 49 kDa

ID gène: 57708

NCBI Accession: NM_020948, NP_065999

UniProt: Q8NES5

Pathways: Chromatin Binding