TFB2M anticorps (N-Term)

N° du produit ABIN2775816

L’anticorps Lapin Polyclonal anti-TFB2M a été validé pour WB et IHC. Il convient pour détecter TFB2M dans des échantillons de Humain, Rat, Cheval et Lapin.

Aperçu rapide pour TFB2M anticorps (N-Term) (ABIN2775816)

Antigène: TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))

Reactivité: Humain, Rat, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFB2M est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-TFB2M anticorps

Épitope: N-Term

Séquence: ECNPGPGILT QALLEAGAKV VALESDKTFI PHLESLGKNL DGKLRVIHCD

Homologie: Horse: 100%, Human: 100%, Rabbit: 83%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against TFB2M. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TFB2M

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 396 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TFB2M

Antigène: TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))

Autre désignation: TFB2M

Sujet: TFB2M is a S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. It is also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. It stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
Alias Symbols: FLJ22661, FLJ23182, Hkp1, mtTFB2
Protein Interaction Partner: UBC, FBXO6, C1QBP, CUL3, TFB2M, POLRMT, TFAM, PNP,
Protein Size: 396

Poids moléculaire: 45 kDa

ID gène: 64216

NCBI Accession: NM_022366, NP_071761

UniProt: Q9H5Q4