TFB2M anticorps (N-Term)

N° du produit ABIN2775816

Détail du produit anti-TFB2M anticorps

Antigène: TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))

Épitope: N-Term

Reactivité: Humain, Rat, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFB2M est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: ECNPGPGILT QALLEAGAKV VALESDKTFI PHLESLGKNL DGKLRVIHCD

Homologie: Horse: 100%, Human: 100%, Rabbit: 83%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against TFB2M. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TFB2M

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 396 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TFB2M

Antigène: TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))

Autre désignation: TFB2M (TFB2M Produits)

Synonymes: anticorps CG3910, anticorps Dmel\\CG3910, anticorps TFB2, anticorps d-TF2BM, anticorps d-mtTFB2, anticorps TFB2M, anticorps sb:cb857, anticorps hkp1, anticorps Hkp1, anticorps mtTFB2, anticorps mitochondrial transcription factor B2, anticorps transcription factor B2, mitochondrial, anticorps mtTFB2, anticorps TFB2M, anticorps tfb2m, anticorps Tfb2m

Sujet: TFB2M is a S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. It is also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. It stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
Alias Symbols: FLJ22661, FLJ23182, Hkp1, mtTFB2
Protein Interaction Partner: UBC, FBXO6, C1QBP, CUL3, TFB2M, POLRMT, TFAM, PNP,
Protein Size: 396

Poids moléculaire: 45 kDa

ID gène: 64216

NCBI Accession: NM_022366, NP_071761

UniProt: Q9H5Q4