TFB2M anticorps (N-Term)

N° du produit ABIN2775816

L’anticorps anti-TFB2M Polyclonal Lapin est utilisé pour la détection de TFB2M dans des échantillons de Humain, Rat, Cheval et Lapin. Il a été validé pour WB et IHC.

Aperçu rapide pour TFB2M anticorps (N-Term) (ABIN2775816)

Antigène: TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))

Reactivité: Humain, Rat, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFB2M est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-TFB2M anticorps

Épitope: N-Term

Fonction: TFB2M Antibody - N-terminal region

Séquence: ECNPGPGILT QALLEAGAKV VALESDKTFI PHLESLGKNL DGKLRVIHCD

Homologie: Horse: 100%, Human: 100%, Rabbit: 83%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against TFB2M. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TFB2M

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8114163

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur TFB2M

Antigène: TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))

Autre désignation: TFB2M

Sujet:

Background Information: TFB2M is a S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. It is also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. It stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.

Gene Name: Transcription factor B2, mitochondrial

Alternative Symbols: Hkp1, mtTFB2

Protein Name: Dimethyladenosine transferase 2, mitochondrial

Poids moléculaire: 45kDa

ID gène: 64216

NCBI Accession: NP_071761

UniProt: Q9H5Q4