LIN28A anticorps (N-Term)

N° du produit ABIN2775818

L’anticorps Lapin Polyclonal anti-LIN28A a été validé pour WB et IHC. Il convient pour détecter LIN28A dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Mouton, Chévre, Cobaye, Lapin et Saccharomyces cerevisiae.

Aperçu rapide pour LIN28A anticorps (N-Term) (ABIN2775818)

Antigène: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Mouton, Chévre, Cobaye, Lapin, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIN28A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-LIN28A anticorps

Épitope: N-Term

Séquence: GSVSNQQFAG GCAKAAEEAP EEAPEDAARA ADEPQLLHGA GICKWFNVRM

Homologie: Cow: 100%, Dog: 100%, Goat: 91%, Guinea Pig: 86%, Human: 100%, Mouse: 90%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 77%

Attributs du produit: This is a rabbit polyclonal antibody against LIN28. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human LIN28

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 209 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur LIN28A

Antigène: LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))

Autre désignation: LIN28

Sujet: LIN28 acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. The association of LIN28 with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. IT binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. LIN28 is Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression.
Alias Symbols: CSDD1, FLJ12457, LIN-28, LIN28A, ZCCHC1, LIN28, lin-28A
Protein Interaction Partner: HNRNPUL2, HNRNPA3, DHX36, SREK1, TRIM71, LARP4, TGS1, DHX57, GADD45GIP1, LTV1, NOA1, DDX50, KRI1, NOL6, METTL17, NOC3L, ZC3HAV1, PPAN, CCBL2, MEPCE, TSR1, NHP2, NOP10, STRBP, BRIX1, RBM28, PHAX, SRRT, LARP7, DDX41, HP1BP3, NOB1, PRPF19, ZBTB11, SND1, AATF
Protein Size: 209

Poids moléculaire: 23 kDa

ID gène: 79727

NCBI Accession: NM_024674, NP_078950

UniProt: Q9H9Z2

Pathways: Stem Cell Maintenance