LIN28A anticorps (N-Term)
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- Antigène Voir toutes LIN28A Anticorps
- LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
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Épitope
- N-Term
- Reactivité
- Humain, Souris, Rat, Porc, Boeuf (Vache), Chien, Mouton, Lapin, Saccharomyces cerevisiae, Chévre, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LIN28A est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- GSVSNQQFAG GCAKAAEEAP EEAPEDAARA ADEPQLLHGA GICKWFNVRM
- Homologie
- Cow: 100%, Dog: 100%, Goat: 91%, Guinea Pig: 86%, Human: 100%, Mouse: 90%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 77%
- Attributs du produit
- This is a rabbit polyclonal antibody against LIN28. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human LIN28
- Top Product
- Discover our top product LIN28A Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 209 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
- Autre désignation
- LIN28 (LIN28A Produits)
- Synonymes
- anticorps CSDD1, anticorps LIN-28, anticorps LIN28, anticorps ZCCHC1, anticorps lin-28A, anticorps AL024421, anticorps ENSMUSG00000070700, anticorps Gm10299, anticorps Lin-28, anticorps Lin28, anticorps Tex17, anticorps csdd1, anticorps lin-28, anticorps lin28, anticorps zcchc1, anticorps sb:cb650, anticorps zgc:55584, anticorps RGD1566408, anticorps lin-28 homolog A, anticorps lin-28 homolog A (C. elegans), anticorps lin-28 homolog A S homeolog, anticorps LIN28A, anticorps Lin28a, anticorps lin28a.S, anticorps lin28a
- Sujet
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LIN28 acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. The association of LIN28 with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. IT binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. LIN28 is Essential for skeletal muscle differentiation program through the translational up-regulation of IGF2 expression.
Alias Symbols: CSDD1, FLJ12457, LIN-28, LIN28A, ZCCHC1, LIN28, lin-28A
Protein Interaction Partner: HNRNPUL2, HNRNPA3, DHX36, SREK1, TRIM71, LARP4, TGS1, DHX57, GADD45GIP1, LTV1, NOA1, DDX50, KRI1, NOL6, METTL17, NOC3L, ZC3HAV1, PPAN, CCBL2, MEPCE, TSR1, NHP2, NOP10, STRBP, BRIX1, RBM28, PHAX, SRRT, LARP7, DDX41, HP1BP3, NOB1, PRPF19, ZBTB11, SND1, AATF
Protein Size: 209 - Poids moléculaire
- 23 kDa
- ID gène
- 79727
- NCBI Accession
- NM_024674, NP_078950
- UniProt
- Q9H9Z2
- Pathways
- Stem Cell Maintenance
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