SUV420H1 anticorps (Middle Region)

N° du produit ABIN2775877

Cité dans 3 publications. Cet anticorps anti-SUV420H1 Polyclonal Lapin (ABIN2775877) détecte spécifiquement SUV420H1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Cobaye et Cheval.

Aperçu rapide pour SUV420H1 anticorps (Middle Region) (ABIN2775877)

Antigène: SUV420H1 (Suppressor of Variegation 4-20 Homolog 1 (SUV420H1))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUV420H1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SUV420H1 anticorps

Épitope: Middle Region

Fonction: KMT5B Antibody - middle region

Séquence: NNGFNSGSGS SSTKLKIQLK RDEENRGSYT EGLHENGVCC SDPLSLLESR

Homologie: Dog: 86%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 91%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SUV420H1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SUV420H1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8113125

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SUV420H1 (ABIN2775877)

Murata, Kondo, Sugimoto, Kawashima, Saito, Isomura, Kanda, Tsurumi: "Epigenetic histone modification of Epstein-Barr virus BZLF1 promoter during latency and reactivation in Raji cells." dans: Journal of virology, Vol. 86, Issue 9, pp. 4752-61, (2012) (PubMed).

Gatta, Mantovani: "NF-Y substitutes H2A-H2B on active cell-cycle promoters: recruitment of CoREST-KDM1 and fine-tuning of H3 methylations." dans: Nucleic acids research, Vol. 36, Issue 20, pp. 6592-607, (2008) (PubMed).

Twells, Metzker, Brown, Cox, Garey, Hammond, Hey, Levy, Nakagawa, Philips, Todd, Hess: "The sequence and gene characterization of a 400-kb candidate region for IDDM4 on chromosome 11q13." dans: Genomics, Vol. 72, Issue 3, pp. 231-42, (2001) (PubMed).

Détails sur SUV420H1

Antigène: SUV420H1 (Suppressor of Variegation 4-20 Homolog 1 (SUV420H1))

Autre désignation: KMT5B

Sujet:

Background Information: This gene encodes a protein that contains a SET domain. SET domains appear to be protein-protein interaction domains that mediate interactions with a family of proteins that display similarity with dual-specificity phosphatases (dsPTPases). The function of this gene has not been determined. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: lysine methyltransferase 5B

Alternative Symbols: CGI85, MRD51, CGI-85, SUV420H1

Protein Name: histone-lysine N-methyltransferase KMT5B

Poids moléculaire: 99 kDa

ID gène: 51111

UniProt: Q4FZB7