HDAC8 anticorps (C-Term)

N° du produit ABIN2775890

Cet anticorps Lapin Polyclonal détecte spécifiquement HDAC8 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval, Porc et Poisson zèbre (Danio rerio).

Aperçu rapide pour HDAC8 anticorps (C-Term) (ABIN2775890)

Antigène: HDAC8 (Histone Deacetylase 8 (HDAC8))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval, Porc, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-HDAC8 anticorps

Épitope: C-Term

Séquence: TGVILGKTLS SEIPDHEFFT AYGPDYVLEI TPSCRPDRNE PHRIQQILNY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against HDAC8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human HDAC8

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 377 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur HDAC8

Antigène: HDAC8 (Histone Deacetylase 8 (HDAC8))

Autre désignation: HDAC8

Sujet: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HDACL1, RPD3, HD8, CDA07
Protein Interaction Partner: MDM1, HDAC8, ZSCAN2, CHCHD3, STAG2, SEC16A, CROCC, SMC3, CPNE3, SMC1A, TPM4, TPM3, SVIL, NUP98, MME, ADD3, SMG5, SMG6, HSP90AA1, HSPA4, HIST4H4, HIST3H3, UBC, PRKACA, HIST1H4A, HIST1H3A, ESRRA, ACTA1, RTN1, PPP1CC, CREB1, HIST2H4A, RUNX1T1, CBFA2T3, MDC1,
Protein Size: 377

Poids moléculaire: 42 kDa

ID gène: 55869

NCBI Accession: NM_018486, NP_060956

UniProt: Q9BY41

Pathways: Cellular Glucan Metabolic Process