Angiomotin anticorps (N-Term)

N° du produit ABIN2775938

Cet anticorps Lapin Polyclonal détecte spécifiquement Angiomotin dans WB. Il présente une réactivité envers Humain, Souris, Rat, Cheval, Chien, Cobaye, Lapin et Boeuf (Vache).

Aperçu rapide pour Angiomotin anticorps (N-Term) (ABIN2775938)

Antigène: Angiomotin (AMOT)

Reactivité: Humain, Souris, Rat, Cheval, Chien, Cobaye, Lapin, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiomotin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Angiomotin anticorps

Épitope: N-Term

Séquence: TANKQLAEKE YEGSEDTRKT ISQLFAKNKE SQREKEKLEA ELATARSTNE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against AMOT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human AMOT

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 675 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Angiomotin

Antigène: Angiomotin (AMOT)

Autre désignation: AMOT

Sujet: AMOT belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: KIAA1071
Protein Interaction Partner: AMOT, C1orf216, WDYHV1, MED4, SNAPC5, PPP2R4, LURAP1, UNC119, LMO4, PIN1, MAGEA4, KRT31, KRT15, FUS, SEPT1, CEP76, HAUS2, LATS2, CEP250, CDKN1A, ACTB, ACTA1, YAP1, SART3, AURKB, MAPK3, BAG3, WWOX, ITCH, LATS1, YWHAG, UBC, PARK2, AMOTL1, SPICE1, MPP7, CNTR
Protein Size: 675

Poids moléculaire: 72 kDa

ID gène: 154796

NCBI Accession: NM_133265, NP_573572

UniProt: Q4VCS5

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size