MID1 anticorps (C-Term)

N° du produit ABIN2775948

Détail du produit anti-MID1 anticorps

Antigène: MID1 (Midline 1 (MID1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MID1 est non-conjugé

Application: Western Blotting (WB)

Séquence: AINQAGSRSS EPGKLKTNSQ PFKLDPKSAH RKLKVSHDNL TVERDESSSK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MID1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human MID1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 667 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MID1

Antigène: MID1 (Midline 1 (MID1))

Autre désignation: MID1 (MID1 Produits)

Synonymes: anticorps BBBG1, anticorps FXY, anticorps GBBB1, anticorps MIDIN, anticorps OGS1, anticorps OS, anticorps OSX, anticorps RNF59, anticorps TRIM18, anticorps XPRF, anticorps ZNFXY, anticorps 61B3-R, anticorps DXHXS1141, anticorps Fxy, anticorps Trim18, anticorps Midline1, anticorps bbbg1, anticorps fxy, anticorps gbbb1, anticorps midin, anticorps ogs1, anticorps osx, anticorps rnf59, anticorps trim18, anticorps xprf, anticorps znfxy, anticorps midline 1, anticorps midline 1 L homeolog, anticorps MID1, anticorps Mid1, anticorps mid1, anticorps mid1.L

Sujet: MID1 is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Several different transcript variants are generated by alternate splicing, however, the full length nature of two variants has not been determined.
Alias Symbols: OS, FXY, OSX, OGS1, XPRF, BBBG1, GBBB1, MIDIN, RNF59, ZNFXY, TRIM18
Protein Interaction Partner: STK36, MID2, UBE2E3, DYRK4, UBE2E2, UBE2E1, UBE2D3, UBE2D2, UBE2D1, PKN1, PPP2R4, PPP2CA, MID1, MEOX1, FKBP1A, EHHADH, BYSL, TCEANC, UBTD1, OTUB2, GMCL1, HTT, IGBP1, PNKP, MID1IP1, GNB2L1, RPS8, RPS3, NPM1, HSP90AA1, EEF1A1, ANXA2, UBC, UBE2D4, UBE2N, ELA
Protein Size: 667

Poids moléculaire: 75 kDa

ID gène: 4281

NCBI Accession: NM_000381, NP_000372

UniProt: O15344