PAX5 anticorps (N-Term)
Aperçu rapide pour PAX5 anticorps (N-Term) (ABIN2775953)
Antigène
Voir toutes PAX5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- CVSKILGRYY ETGSIKPGVI GGSKPKVATP KVVEKIAEYK RQNPTMFAWE
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against PAX5. It was validated on Western Blot and immunohistochemistry.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human PAX5
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 391 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PAX5 (Paired Box 5 (PAX5))
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Autre désignation
- PAX5
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Sujet
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The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.
Alias Symbols: BSAP
Protein Interaction Partner: TBP, RB1, EP300, RUNX1, TLE4, DAXX, KPNA1, KPNA2, ID2, ID3, CREBBP, MYB, PAX5, ETS1, EBF1,
Protein Size: 391 -
Poids moléculaire
- 42 kDa
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ID gène
- 5079
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NCBI Accession
- NM_016734, NP_057953
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UniProt
- Q02548
Antigène
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