CREM anticorps (C-Term)

N° du produit ABIN2776017

Cet anticorps anti-CREM Polyclonal Lapin (ABIN2776017) détecte spécifiquement CREM dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Mouton et Poisson zèbre (Danio rerio).

Aperçu rapide pour CREM anticorps (C-Term) (ABIN2776017)

Antigène: CREM (CAMP Responsive Element Modulator (CREM))

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Mouton, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CREM est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CREM anticorps

Épitope: C-Term

Fonction: Crem Antibody - C-terminal region

Séquence: KNREAARECR RKKKEYVKCL ENRVAVLENQ NKTLIEELKA LKDLYCHKAE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Crem. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Rat Crem

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34778-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CREM

Antigène: CREM (CAMP Responsive Element Modulator (CREM))

Autre désignation: Crem

Sujet:

Background Information: Crem is a transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Isoform Delta is an activator. Crem plays a role in spermatogenesis and is involved in spermatid maturation. Binding of isoform Tau (activator) to CRE is increased by CREB3L4. The CREM isoform Tau-CREB3L4 heterodimer functions through CRE and may recruit HIRA to CRE to regulate histone exchange.

Alternative Symbols: Icer

Protein Name: cAMP-responsive element modulator

Poids moléculaire: 37 kDa

ID gène: 25620

NCBI Accession: NP_001104330

UniProt: Q03061

Pathways: Retinoic Acid Receptor Signaling Pathway