PKD2 anticorps (N-Term)

N° du produit ABIN2776087

Détail du produit anti-PKD2 anticorps

Antigène: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKD2 est non-conjugé

Application: Western Blotting (WB)

Séquence: GLRGLWGTRL MEESSTNREK YLKSVLRELV TYLLFLIVLC ILTYGMMSSN

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PKD2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PKD2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PKD2

Antigène: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Autre désignation: PKD2 (PKD2 Produits)

Synonymes: anticorps APKD2, anticorps PC2, anticorps PKD4, anticorps Pc-2, anticorps TRPP2, anticorps C030034P18Rik, anticorps RGD1559992, anticorps pkd2, anticorps trpp2, anticorps Cup, anticorps PKD2L1, anticorps polycystin 2, transient receptor potential cation channel, anticorps polycystic kidney disease 2, anticorps Polycystin-2, anticorps polycystin 2, transient receptor potential cation channel L homeolog, anticorps PKD2, anticorps Pkd2, anticorps pkd-2, anticorps pkd2.L, anticorps pkd2

Sujet: This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.
Protein Interaction Partner: MAGEA8, PLSCR1, KRTAP10-3, KRTAP10-8, KRT40, PKD1, GOLGA2, CANX, ATP1A1, UBC, PACS2, HAX1, TRPC1, TNNI3, PACS1, CD2AP, DIAPH1, TPM1, PKD2, ACTN2,
Protein Size: 646

Poids moléculaire: 71 kDa

ID gène: 5311

Pathways: cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity