SCN7A anticorps (N-Term)

N° du produit ABIN2776152

Cet anticorps Lapin Polyclonal détecte spécifiquement SCN7A dans WB. Il présente une réactivité avec des échantillons de Humain, Rat, Souris, Chien et Cobaye.

Aperçu rapide pour SCN7A anticorps (N-Term) (ABIN2776152)

Antigène: SCN7A (Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A))

Reactivité: Humain, Rat, Souris, Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCN7A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SCN7A anticorps

Épitope: N-Term

Séquence: PFIYGNLSQG MVSEPLEDVD PYYYKKKNTF IVLNKNRTIF RFNAASILCT

Homologie: Dog: 79%, Guinea Pig: 80%, Human: 100%, Mouse: 79%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against SCN7A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of human SCN7A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SCN7A

Antigène: SCN7A (Sodium Channel, Voltage-Gated, Type VII, alpha Subunit (SCN7A))

Autre désignation: SCN7A

Sujet: This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics, the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels, domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown.
Alias Symbols: NaG, SCN6A, Nav2.1, Nav2.2
Protein Size: 762

Poids moléculaire: 83 kDa

ID gène: 6332

NCBI Accession: NM_002976, NP_002967

UniProt: Q01118