CLCNKA anticorps (N-Term)
Aperçu rapide pour CLCNKA anticorps (N-Term) (ABIN2776159)
Antigène
Voir toutes CLCNKA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- CLCNKA Antibody - N-terminal region
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Séquence
- MEELVGLREG FSGDPVTLQE LWGPCPHIRR AIQGGLEWLK QKVFRLGEDW
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Homologie
- Cow: 90%, Human: 100%, Mouse: 85%, Pig: 85%, Rat: 85%
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Attributs du produit
- This is a rabbit polyclonal antibody against CLCNKA. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human CLCNKA
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP35132-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- CLCNKA (Chloride Channel Ka (CLCNKA))
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Autre désignation
- CLCNKA
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Sujet
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Background Information: CLCNKA is a member of the CLC family of voltage-gated chloride channels. It is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Name: Chloride channel, voltage-sensitive Ka
Alternative Symbols: CLCK1, ClC-K1, hClC-Ka
Protein Name: Chloride channel protein ClC-Ka
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Poids moléculaire
- 75kDa
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ID gène
- 1187
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NCBI Accession
- NP_004061
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UniProt
- P51800
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Pathways
- Response to Water Deprivation
Antigène
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