ASIC3 anticorps (N-Term)

N° du produit ABIN2776167

Cet anticorps anti-ASIC3 Polyclonal Lapin (ABIN2776167) détecte spécifiquement ASIC3 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Porc.

Aperçu rapide pour ASIC3 anticorps (N-Term) (ABIN2776167)

Antigène: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASIC3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-ASIC3 anticorps

Épitope: N-Term

Fonction: ACCN3 Antibody - N-terminal region

Séquence: VATFLYQVAE RVRYYREFHH QTALDERESH RLIFPAVTLC NINPLRRSRL

Homologie: Cow: 80%, Dog: 80%, Guinea Pig: 80%, Horse: 80%, Human: 100%, Mouse: 87%, Pig: 87%, Rabbit: 87%, Rat: 87%

Attributs du produit: This is a rabbit polyclonal antibody against ACCN3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ACCN3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP35152-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur ASIC3

Antigène: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Autre désignation: ACCN3

Sujet:

Background Information: ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.

Gene Name: Acid-sensing (proton-gated) ion channel 3

Alternative Symbols: ACCN3, TNaC1, DRASIC, SLNAC1

Protein Name: Acid-sensing ion channel 3

Poids moléculaire: 58kDa

ID gène: 9311

NCBI Accession: NP_004760

UniProt: Q9UHC3