GRIK2 anticorps (N-Term)

N° du produit ABIN2776332

Cet anticorps Lapin Polyclonal détecte spécifiquement GRIK2 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio) et a été mentionné dans 2+ publications.

Aperçu rapide pour GRIK2 anticorps (N-Term) (ABIN2776332)

Antigène: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIK2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-GRIK2 anticorps

Épitope: N-Term

Séquence: PDFSSLSRAI LDLVQFFKWK TVTVVYDDST GLIRLQELIK APSRYNLRLK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against GRIK2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GRIK2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 908 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-GRIK2 (ABIN2776332)

Funk, Janech, Dillon, Bissler, Siroky, Bell: "Characterization of renal toxicity in mice administered the marine biotoxin domoic Acid." dans: Journal of the American Society of Nephrology : JASN, Vol. 25, Issue 6, pp. 1187-97, (2014) (PubMed).

Delorme, Krebs, Chabane, Roy, Millet, Mouren-Simeoni, Maier, Bourgeron, Leboyer: "Frequency and transmission of glutamate receptors GRIK2 and GRIK3 polymorphisms in patients with obsessive compulsive disorder." dans: Neuroreport, Vol. 15, Issue 4, pp. 699-702, (2004) (PubMed).

Détails sur GRIK2

Antigène: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Autre désignation: GRIK2

Sujet: The GRIK2 gene encodes a subunit of a kainate glutamate receptor. Glutamate receptors mediate the majority of excitatory neurotransmission in the brain. This receptor may have a role in synaptic plasticity and may be important for learning and memory. It also may be involved in the transmission of light information from the retina to the hypothalamus. The structure and function of the encoded protein is changed by RNA editing.
Protein Interaction Partner: CALCOCO1, TRIM25, PICK1, DLG4, LIN7B, GRID2, PRKAA1, SDCBP, CTNND1, DLG1, GRIK5, GRIK4, DLG3, CASK, GRIA1, GRIK2, CTNNB1, CDH2, GRIP1, GRIA2,
Protein Size: 908

Poids moléculaire: 102 kDa

ID gène: 2898

UniProt: Q13002

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity