KLF6 anticorps (Middle Region)

N° du produit ABIN2776377

L’anticorps Lapin Polyclonal anti-KLF6 a été validé pour WB. Il convient pour détecter KLF6 dans des échantillons de Humain, Souris, Rat, Chien, Cheval, Cobaye, Lapin et Boeuf (Vache).

Aperçu rapide pour KLF6 anticorps (Middle Region) (ABIN2776377)

Antigène: KLF6 (Kruppel-Like Factor 6 (KLF6))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Cobaye, Lapin, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLF6 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KLF6 anticorps

Épitope: Middle Region

Séquence: SREPSQLWGC VPGELPSPGK VRSGTSGKPG DKGNGDASPD GRRRVHRCHF

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against KLF6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human KLF6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 283 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KLF6

Antigène: KLF6 (Kruppel-Like Factor 6 (KLF6))

Autre désignation: KLF6

Sujet: KLF6 is a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. KLF6 may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes.This gene encodes a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: GBF, ZF9, BCD1, CBA1, CPBP, PAC1, ST12, COPEB
Protein Interaction Partner: UBC, APP, LCOR, SP1, NUFIP1, NOP56, TAF9, FBL, HDAC3, E2F1, NR0B2, PNO1, POLA2, GTF3C1, EHMT2, APOM, CELSR2, KLF4, TP53, CCND1,
Protein Size: 283

Poids moléculaire: 32 kDa

ID gène: 1316

NCBI Accession: NM_001300, NP_001291

UniProt: Q99612